Methanol → 7a-(2,3-Difluorophenyl)-5-(trifluoromethyl)-4,4a,5,7-tetrahydrofuro[3,4-d][1,3]thiazin-2-amine
Reaction equation
[CH3:42][OH:43].[F:1][c:2]1[c:3]([C:9]23[N:10]=[C:11]([NH:22][C:23](=[O:24])[c:25]4[cH:26][cH:27][cH:28][cH:29][cH:30]4)[S:12][CH2:13][CH:14]2[CH:15]([C:18]([F:19])([F:20])[F:21])[O:16][CH2:17]3)[cH:4][cH:5][cH:6][c:7]1[F:8].[N:31]12[CH2:32][CH2:33][CH2:34][N:35]=[C:36]1[CH2:37][CH2:38][CH2:39][CH2:40][CH2:41]2>>[F:1][c:2]1[c:3]([C:9]23[N:10]=[C:11]([NH2:22])[S:12][CH2:13][CH:14]2[CH:15]([C:18]([F:19])([F:20])[F:21])[O:16][CH2:17]3)[cH:4][cH:5][cH:6][c:7]1[F:8]Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-06bb454f42034aa0a5f3a3dbdb235c70
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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