Dichloromethane → 4-methyl-N-(3-morpholinophenyl)-3-(3-pyrrolidin-3-yloxybenzamido)benzamide

HRID 1146186Notes

Reaction equation

HRID 1146186 reaction equation
[C:8]([O:9][C:10](=[O:11])[N:15]1[CH2:16][CH:17]([O:20][c:21]2[cH:22][c:23]([C:24](=[O:25])[NH:26][c:27]3[cH:28][c:29]([C:30](=[O:31])[NH:32][c:33]4[cH:34][c:35]([N:39]5[CH2:40][CH2:41][O:42][CH2:43][CH2:44]5)[cH:36][cH:37][cH:38]4)[cH:45][cH:46][c:47]3[CH3:48])[cH:49][cH:50][cH:51]2)[CH2:18][CH2:19]1)([CH3:12])([CH3:13])[CH3:14].[CH2:52]([Cl:53])[Cl:54].[OH:1][C:2]([C:3]([F:4])([F:5])[F:6])=[O:7]>>[NH:15]1[CH2:16][CH:17]([O:20][c:21]2[cH:22][c:23]([C:24](=[O:25])[NH:26][c:27]3[cH:28][c:29]([C:30](=[O:31])[NH:32][c:33]4[cH:34][c:35]([N:39]5[CH2:40][CH2:41][O:42][CH2:43][CH2:44]5)[cH:36][cH:37][cH:38]4)[cH:45][cH:46][c:47]3[CH3:48])[cH:49][cH:50][cH:51]2)[CH2:18][CH2:19]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 226361163-[3-(1-tert-butoxycarbonylpyrrolidin-3-yloxy)benzamido]-4-methyl-N-(3-morpholinophenyl)benzamide

Product 1

HCID 226361154-methyl-N-(3-morpholinophenyl)-3-(3-pyrrolidin-3-yloxybenzamido)benzamide

Sources & evidence

ORD record
ord-c36c91ec4fe845c2adc650867cfd7e07
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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