Acetonitrile → 7-[6-(4-Trifluoromethyl-phenyl)-pyrimidin-4-yloxy]-1H-quinolin-2-one
Reaction equation
[CH3:41][C:42]#[N:43].[Cl:1][c:2]1[n:3][cH:4][n:5][c:6](-[c:8]2[cH:9][cH:10][c:11]([C:14]([F:15])([F:16])[F:17])[cH:12][cH:13]2)[cH:7]1.[N:30]12[CH2:31][CH2:32][CH2:33][N:34]=[C:35]1[CH2:36][CH2:37][CH2:38][CH2:39][CH2:40]2.[OH:18][c:19]1[cH:20][cH:21][c:22]2[cH:23][cH:24][c:25](=[O:29])[nH:26][c:27]2[cH:28]1>>[c:2]1([O:18][c:19]2[cH:20][cH:21][c:22]3[cH:23][cH:24][c:25](=[O:29])[nH:26][c:27]3[cH:28]2)[n:3][cH:4][n:5][c:6](-[c:8]2[cH:9][cH:10][c:11]([C:14]([F:15])([F:16])[F:17])[cH:12][cH:13]2)[cH:7]1Participants
5
Sources & evidence
- ORD record
- ord-c088e9ba63ab4cf48c58039aa3b00a51
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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