1,4-Dibromobenzene → 1-(4-Bromophenyl)cyclobutanol

HRID 1146978Notes

Reaction equation

HRID 1146978 reaction equation
[Br:6][c:7]1[cH:8][cH:9][c:10]([Br:11])[cH:12][cH:13]1.[C:14]1(=[O:18])[CH2:15][CH2:16][CH2:17]1.[CH2:19]1[O:20][CH2:21][CH2:22][CH2:23]1.[CH2:1]([Li:2])[CH2:3][CH2:4][CH3:5]>>[c:7]1([C:14]2([OH:18])[CH2:15][CH2:16][CH2:17]2)[cH:8][cH:9][c:10]([Br:11])[cH:12][cH:13]1

Participants

5

Reactant 4

HCID 78041,4-DibromobenzeneHCID 8028TetrahydrofuranHCID 14496CyclobutanoneHCID 178418339Butyllithium

Product 1

HCID 120954191-(4-Bromophenyl)cyclobutanol

Sources & evidence

ORD record
ord-65a177e2a55f4c9da997484977fdf730
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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