N-methyl-2-pyrrolidone → N-[2-chloro-3-({2-[(cyclopropylcarbonyl)amino]imidazo[1,2-b]pyridazin-6-yl}oxy)-4-methylphenyl]-3-(trifluoromethyl)benzamide
Reaction equation
[CH3:39][N:40]1[CH2:41][CH2:42][CH2:43][C:44]1=[O:45].[F:26][C:27]([c:28]1[cH:29][c:30]([C:31](=[O:32])[Cl:33])[cH:34][cH:35][cH:36]1)([F:37])[F:38].[NH2:1][c:2]1[c:3]([Cl:25])[c:4]([O:5][c:6]2[cH:7][cH:8][c:9]3[n:10]([n:11]2)[cH:12][c:13]([NH:15][C:16](=[O:17])[CH:18]2[CH2:19][CH2:20]2)[n:14]3)[c:21]([CH3:24])[cH:22][cH:23]1>>[NH:1]([c:2]1[c:3]([Cl:25])[c:4]([O:5][c:6]2[cH:7][cH:8][c:9]3[n:10]([n:11]2)[cH:12][c:13]([NH:15][C:16](=[O:17])[CH:18]2[CH2:19][CH2:20]2)[n:14]3)[c:21]([CH3:24])[cH:22][cH:23]1)[C:31]([c:30]1[cH:29][c:28]([C:27]([F:26])([F:37])[F:38])[cH:36][cH:35][cH:34]1)=[O:32]Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-d8962dc7b4104227a1f0cb01f8a5401e
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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