Hydrochloric Acid → Isopropyl 4-{2-[2-amino-6-(4-methylpiperazin-1-yl)pyrimidin-4-yl]-3-methyl-1,2,3,4-tetrahydroisoquinolin-7-yl}piperidine-1-carboxylate

HRID 1147372Notes

Reaction equation

HRID 1147372 reaction equation
[CH3:1][N:2]1[CH2:3][CH2:4][N:5]([c:8]2[n:9][c:10]([NH2:31])[n:11][c:12]([N:14]3[CH2:15][c:16]4[cH:17][c:18]([CH:25]5[CH2:26][CH2:27][NH:28][CH2:29][CH2:30]5)[cH:19][cH:20][c:21]4[CH2:22][CH:23]3[CH3:24])[cH:13]2)[CH2:6][CH2:7]1.[Cl:33][C:34](=[O:35])[O:36][CH:37]([CH3:38])[CH3:39].[ClH:32]>>[CH3:1][N:2]1[CH2:3][CH2:4][N:5]([c:8]2[n:9][c:10]([NH2:31])[n:11][c:12]([N:14]3[CH2:15][c:16]4[cH:17][c:18]([CH:25]5[CH2:26][CH2:27][N:28]([C:34](=[O:35])[O:36][CH:37]([CH3:38])[CH3:39])[CH2:29][CH2:30]5)[cH:19][cH:20][c:21]4[CH2:22][CH:23]3[CH3:24])[cH:13]2)[CH2:6][CH2:7]1

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 7917Isopropyl chloroformateHCID 59402258HCID 59402258, compound

Product 1

HCID 59402362Isopropyl 4-{2-[2-amino-6-(4-methylpiperazin-1-yl)pyrimidin-4-yl]-3-methyl-1,2,3,4-tetrahydroisoquinolin-7-yl}piperidine-1-carboxylate

Sources & evidence

ORD record
ord-f7555bd1c3b94d178f733627b8554a1e
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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