Dichloromethane → Phenylmethyl 2-cyano-3,3-dimethyl-1-pyrrolidinecarboxylate

HRID 1147520Notes

Reaction equation

HRID 1147520 reaction equation
[CH2:26]([Cl:27])[Cl:28].[CH3:1][C:2]1([CH3:19])[CH:3]([O:17][CH3:18])[N:4]([C:7](=[O:8])[O:9][CH2:10][c:11]2[cH:12][cH:13][cH:14][cH:15][cH:16]2)[CH2:5][CH2:6]1.[CH3:20][Si:21]([CH3:22])([CH3:23])[C:24]#[N:25]>>[CH3:1][C:2]1([CH3:19])[CH:3]([C:24]#[N:25])[N:4]([C:7](=[O:8])[O:9][CH2:10][c:11]2[cH:12][cH:13][cH:14][cH:15][cH:16]2)[CH2:5][CH2:6]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 82115Trimethylsilyl cyanideHCID 57878094Phenylmethyl 3,3-dimethyl-2-(methyloxy)-1-pyrrolidinecarboxylate

Product 1

HCID 57878087Phenylmethyl 2-cyano-3,3-dimethyl-1-pyrrolidinecarboxylate

Sources & evidence

ORD record
ord-c783b2b2210247bd9a6f5bb3ba315fce
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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