Dichloromethane → HCID 178509624, compound

HRID 1147577Notes

Reaction equation

HRID 1147577 reaction equation
[Br:1][c:2]1[c:3]([N:4]2[CH2:5][CH2:6][N:7]([CH2:8][c:9]3[cH:10][n:11][cH:12][cH:13][cH:14]3)[CH2:15][CH2:16]2)[c:17]2[n:18][c:19](-[c:20]3[cH:21][cH:22][c:23]([CH2:24][NH2:25])[cH:26][cH:27]3)[nH:28][c:29]2[n:30][cH:31]1.[CH2:32]([c:33]1[cH:34][cH:35][cH:36][cH:37][cH:38]1)[CH:39]1[CH2:40][CH2:41][N:42]([c:45]2[c:46]3[c:47]([n:48][cH:49][c:50]2[Br:51])[nH:52][c:53](-[c:55]2[cH:56][cH:57][c:58]([CH2:59][NH:60][C:61](=[O:62])[O:63][C:64]([CH3:65])([CH3:66])[CH3:67])[cH:68][cH:69]2)[n:54]3)[CH2:43][CH2:44]1.[Cl:77][CH2:78][Cl:79].[F:70][C:71]([F:72])([F:73])[C:74]([OH:75])=[O:76]>>[CH2:32]([c:33]1[cH:34][cH:35][cH:36][cH:37][cH:38]1)[CH:39]1[CH2:40][CH2:41][N:42]([c:45]2[c:46]3[c:47]([n:48][cH:49][c:50]2[Br:51])[nH:52][c:53](-[c:55]2[cH:56][cH:57][c:58]([CH2:59][NH2:60])[cH:68][cH:69]2)[n:54]3)[CH2:43][CH2:44]1

Participants

5

Reactant 4

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 178453032tert-butyl 4-(7-(4-benzylpiperidin-1-yl)-6-bromo-3H-imidazo[4,5-b]pyridin-2-yl)benzylcarbamateHCID 178509626HCID 178509626, compound

Product 1

HCID 178509624HCID 178509624, compound

Sources & evidence

ORD record
ord-c557628cda4243d99a2edebea4a80cc2
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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