Hydrogen Bromide → 6-Carboxy-3-[1-(6,7-dimethoxy-4-quinazolinyl)-4-piperidinyl]-1,2,3,4-tetrahydro-1-methyl-2,4-dioxo-quinazoline
Reaction equation
[Br:39].[C:1]([CH3:2])(=[O:3])[c:4]1[cH:5][c:6]2[c:7](=[O:36])[n:8]([CH:16]3[CH2:17][CH2:18][N:19]([c:22]4[n:23][cH:24][n:25][c:26]5[cH:27][c:28]([O:34][CH3:35])[c:29]([O:32][CH3:33])[cH:30][c:31]45)[CH2:20][CH2:21]3)[c:9](=[O:15])[n:10]([CH3:14])[c:11]2[cH:12][cH:13]1.[CH2:43]1[O:44][CH2:45][CH2:46][O:47][CH2:48]1.[CH:49]([Cl:50])([Cl:51])[Cl:52].[ClH:42].[Na+:41].[OH-:40].[OH:37][Br:38]>>[C:1]([OH:3])([c:4]1[cH:5][c:6]2[c:7](=[O:36])[n:8]([CH:16]3[CH2:17][CH2:18][N:19]([c:22]4[n:23][cH:24][n:25][c:26]5[cH:27][c:28]([O:34][CH3:35])[c:29]([O:32][CH3:33])[cH:30][c:31]45)[CH2:20][CH2:21]3)[c:9](=[O:15])[n:10]([CH3:14])[c:11]2[cH:12][cH:13]1)=[O:37]Participants
9
Reactant 8
Product 1
Sources & evidence
- ORD record
- ord-5ba9bf05123e46b59a436b21dd00aa87
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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