Hydrochloric Acid → 1-Benzyl-4-(1,3-dihydroxyprop-2-ylamino)-piperidine

HRID 1147837Notes

Reaction equation

HRID 1147837 reaction equation
[C:21]([O:22][BH-:23]([O:24][C:25](=[O:26])[CH3:27])[O:28][C:29](=[O:30])[CH3:31])(=[O:32])[CH3:33].[CH2:38]([Cl:39])[Cl:40].[CH2:7]([c:8]1[cH:9][cH:10][cH:11][cH:12][cH:13]1)[N:14]1[CH2:15][CH2:16][C:17](=[O:20])[CH2:18][CH2:19]1.[ClH:35].[NH2:1][CH:2]([CH2:3][OH:4])[CH2:5][OH:6].[Na+:34].[Na+:37].[OH-:36].[OH2:41]>>[NH:1]([CH:2]([CH2:3][OH:4])[CH2:5][OH:6])[CH:17]1[CH2:16][CH2:15][N:14]([CH2:7][c:8]2[cH:9][cH:10][cH:11][cH:12][cH:13]2)[CH2:19][CH2:18]1

Participants

9

Reactant 8

HCID 313Hydrochloric AcidHCID 923Sodium ion2×HCID 961HydroxideHCID 962WaterHCID 6344DichloromethaneHCID 192201-Benzyl-4-piperidoneHCID 68294SerinolHCID 2724942Triacetoxyborohydride

Product 1

HCID 227120471-Benzyl-4-(1,3-dihydroxyprop-2-ylamino)-piperidine

Sources & evidence

ORD record
ord-295a9bf306ef4355828b9e761ee0d1ea
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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