Diethylamine → {4-(3-Chloro-4-fluoro-phenyl)-6-[4-(3-trifluoromethyl-pyridin-2-yl)-piperazin-1-yl]-pyrimidin-2-yl}-diethyl-amine

HRID 1147872Notes

Reaction equation

HRID 1147872 reaction equation
[CH2:32]([CH3:33])[NH:34][CH2:35][CH3:36].[Cl:1][c:2]1[n:3][c:4]([N:16]2[CH2:17][CH2:18][N:19]([c:22]3[n:23][cH:24][cH:25][cH:26][c:27]3[C:28]([F:29])([F:30])[F:31])[CH2:20][CH2:21]2)[cH:5][c:6](-[c:8]2[cH:9][c:10]([Cl:15])[c:11]([F:14])[cH:12][cH:13]2)[n:7]1>>[c:2]1([N:34]([CH2:32][CH3:33])[CH2:35][CH3:36])[n:3][c:4]([N:16]2[CH2:17][CH2:18][N:19]([c:22]3[n:23][cH:24][cH:25][cH:26][c:27]3[C:28]([F:29])([F:30])[F:31])[CH2:20][CH2:21]2)[cH:5][c:6](-[c:8]2[cH:9][c:10]([Cl:15])[c:11]([F:14])[cH:12][cH:13]2)[n:7]1

Participants

3

Reactant 2

HCID 8021DiethylamineHCID 577614902-Chloro-4-(3-chloro-4-fluoro-phenyl)-6-[4-(3-trifluoromethylpyridin-2-yl)-piperazin-1-yl]-pyrimidine

Product 1

HCID 57761560{4-(3-Chloro-4-fluoro-phenyl)-6-[4-(3-trifluoromethyl-pyridin-2-yl)-piperazin-1-yl]-pyrimidin-2-yl}-diethyl-amine

Sources & evidence

ORD record
ord-211b5c553530495787738b632741d09e
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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