Diethyl Ether → 9-(4-Chlorophenyl)-8-(2-chlorophenyl)-6-isopropoxy-9H-purine

HRID 1148033Notes

Reaction equation

HRID 1148033 reaction equation
[C:29](=[O:30])([O-:31])[O-:32].[CH2:40]([O:41][CH2:42][CH3:43])[CH3:44].[CH3:35][N:36]([CH3:37])[CH:38]=[O:39].[Cl:1][c:2]1[cH:3][cH:4][c:5](-[n:8]2[c:9]3[n:10][cH:11][n:12][c:13]([OH:24])[c:14]3[n:15][c:16]2-[c:17]2[c:18]([Cl:23])[cH:19][cH:20][cH:21][cH:22]2)[cH:6][cH:7]1.[Cs+:33].[Cs+:34].[I:25][CH:26]([CH3:27])[CH3:28]>>[Cl:1][c:2]1[cH:3][cH:4][c:5](-[n:8]2[c:9]3[n:10][cH:11][n:12][c:13]([O:24][CH:26]([CH3:27])[CH3:28])[c:14]3[n:15][c:16]2-[c:17]2[c:18]([Cl:23])[cH:19][cH:20][cH:21][cH:22]2)[cH:6][cH:7]1

Participants

7

Reactant 6

HCID 3283Diethyl EtherHCID 6228DimethylformamideHCID 6362Isopropyl iodideHCID 19660Carbonate IonHCID 104967Cesium cation2×HCID 178517925HCID 178517925, compound

Product 1

HCID 219058479-(4-Chlorophenyl)-8-(2-chlorophenyl)-6-isopropoxy-9H-purine

Sources & evidence

ORD record
ord-b8e0cae4be9e4f998563acccbd5a1871
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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