Lithium ion → propan-2-yl 4-[acetyl-[[3,5-bis(trifluoromethyl)phenyl]methyl]amino]-2-methyl-6-(trifluoromethyl)-3,4-dihydro-2H-1,5-naphthyridine-1-carboxylate
Reaction equation
[CH3:42][Si:43]([CH3:44])([CH3:45])[N-:46][Si:47]([CH3:48])([CH3:49])[CH3:50].[CH:1]([CH3:2])([CH3:3])[O:4][C:5](=[O:6])[N:7]1[CH:8]([CH3:25])[CH2:9][CH:10]([NH:21][C:22]([CH3:23])=[O:24])[c:11]2[n:12][c:13]([C:17]([F:18])([F:19])[F:20])[cH:14][cH:15][c:16]21.[F:26][C:27]([c:28]1[cH:29][c:30]([CH2:31][Br:32])[cH:33][c:34]([C:36]([F:37])([F:38])[F:39])[cH:35]1)([F:40])[F:41].[Li+:51]>>[CH:1]([CH3:2])([CH3:3])[O:4][C:5](=[O:6])[N:7]1[CH:8]([CH3:25])[CH2:9][CH:10]([N:21]([C:22]([CH3:23])=[O:24])[CH2:31][c:30]2[cH:29][c:28]([C:27]([F:26])([F:40])[F:41])[cH:35][c:34]([C:36]([F:37])([F:38])[F:39])[cH:33]2)[c:11]2[n:12][c:13]([C:17]([F:18])([F:19])[F:20])[cH:14][cH:15][c:16]21Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-85b8fd44ee6643db80d0392339dc5283
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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