Tetrahydrofuran → Methyl{1-[bis(4-chlorophenyl)methyl]-3-hydroxyazetidin-3-yl}(3,5-difluorophenyl)acetate
Reaction equation
[CH2:45]1[O:46][CH2:47][CH2:48][CH2:49]1.[CH3:39][CH2:40][CH2:41][CH2:42][CH2:43][CH3:44].[Cl:19][c:20]1[cH:21][cH:22][c:23]([CH:26]([N:27]2[CH2:28][C:29](=[O:31])[CH2:30]2)[c:32]2[cH:33][cH:34][c:35]([Cl:38])[cH:36][cH:37]2)[cH:24][cH:25]1.[F:6][c:7]1[cH:8][c:9]([CH2:14][C:15](=[O:16])[O:17][CH3:18])[cH:10][c:11]([F:13])[cH:12]1.[Li:1][CH2:2][CH2:3][CH2:4][CH3:5]>>[F:6][c:7]1[cH:8][c:9]([CH:14]([C:15](=[O:16])[O:17][CH3:18])[C:29]2([OH:31])[CH2:28][N:27]([CH:26]([c:23]3[cH:22][cH:21][c:20]([Cl:19])[cH:25][cH:24]3)[c:32]3[cH:33][cH:34][c:35]([Cl:38])[cH:36][cH:37]3)[CH2:30]2)[cH:10][c:11]([F:13])[cH:12]1Participants
6
Sources & evidence
- ORD record
- ord-175f4662ace3401f8118d227997bb502
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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