Dimethylformamide → (4-Fluoro-phenyl)-(5-iodo-imidazo[2,1-b][1,3,4]thiadiazol-2-yl)-amine

HRID 1148319Notes

Reaction equation

HRID 1148319 reaction equation
[CH3:25][N:26]([CH3:27])[CH:28]=[O:29].[F:1][c:2]1[cH:3][cH:4][c:5]([NH:8][c:9]2[n:10][n:11]3[c:12]([s:13]2)[n:14][cH:15][cH:16]3)[cH:6][cH:7]1.[I:17][N:18]1[C:19](=[O:20])[CH2:21][CH2:22][C:23]1=[O:24]>>[F:1][c:2]1[cH:3][cH:4][c:5]([NH:8][c:9]2[n:10][n:11]3[c:12]([s:13]2)[n:14][cH:15][c:16]3[I:17])[cH:6][cH:7]1

Participants

4

Reactant 3

HCID 6228DimethylformamideHCID 120273N-IodosuccinimideHCID 67335853(4-Fluoro-phenyl)-imidazo[2,1-b][1,3,4]thiadiazol-2-yl-amine

Product 1

HCID 67334575(4-Fluoro-phenyl)-(5-iodo-imidazo[2,1-b][1,3,4]thiadiazol-2-yl)-amine

Sources & evidence

ORD record
ord-40e895c4f8594fd8a44220182bfcbd0a
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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