Tetrahydrofuran → 3-[1-[3-(4-ethyl-2-pyridinyl)-4-(7-methyl-1H-indazol-5-yl)butanoyl]piperidin-4-yl]-1,4-dihydroquinazolin-2-one
Reaction equation
[CH2:1]([CH3:2])[c:3]1[cH:4][c:5]([CH:9]([CH2:10][C:11](=[O:12])[N:13]2[CH2:14][CH2:15][CH:16]([N:19]3[C:20](=[O:29])[NH:21][c:22]4[cH:23][cH:24][cH:25][cH:26][c:27]4[CH2:28]3)[CH2:17][CH2:18]2)[CH2:30][c:31]2[cH:32][c:33]3[cH:34][n:35]([CH2:41][O:42][CH2:43][CH2:44][Si:45]([CH3:46])([CH3:47])[CH3:48])[n:36][c:37]3[c:38]([CH3:40])[cH:39]2)[n:6][cH:7][cH:8]1.[CH3:50][CH2:51][CH2:52][CH2:53][N+:54]([CH2:55][CH2:56][CH2:57][CH3:58])([CH2:59][CH2:60][CH2:61][CH3:62])[CH2:63][CH2:64][CH2:65][CH3:66].[F-:49].[O:67]1[CH2:68][CH2:69][CH2:70][CH2:71]1>>[CH2:1]([CH3:2])[c:3]1[cH:4][c:5]([CH:9]([CH2:10][C:11](=[O:12])[N:13]2[CH2:14][CH2:15][CH:16]([N:19]3[C:20](=[O:29])[NH:21][c:22]4[cH:23][cH:24][cH:25][cH:26][c:27]4[CH2:28]3)[CH2:17][CH2:18]2)[CH2:30][c:31]2[cH:32][c:33]3[cH:34][n:35][nH:36][c:37]3[c:38]([CH3:40])[cH:39]2)[n:6][cH:7][cH:8]1Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-bb6d83d0e58d41e5b92b3a0f207c1a7a
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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