Dichloromethane → 2-Methyl-4-phenyl-2,8-diazaspiro[4.6]undecan-1-one

HRID 1148975Notes

Reaction equation

HRID 1148975 reaction equation
[CH3:1][N:2]1[C:3](=[O:26])[C:4]2([CH:5]([c:7]3[cH:8][cH:9][cH:10][cH:11][cH:12]3)[CH2:6]1)[CH2:13][CH2:14][N:15]([C:19]([O:20][C:21]([CH3:22])([CH3:23])[CH3:24])=[O:25])[CH2:16][CH2:17][CH2:18]2.[Cl:34][CH2:35][Cl:36].[F:27][C:28]([F:29])([F:30])[C:31]([OH:32])=[O:33]>>[CH3:1][N:2]1[C:3](=[O:26])[C:4]2([CH:5]([c:7]3[cH:8][cH:9][cH:10][cH:11][cH:12]3)[CH2:6]1)[CH2:13][CH2:14][NH:15][CH2:16][CH2:17][CH2:18]2

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 71060314Tert-butyl 2-methyl-1-oxo-4-phenyl-2,8-diazaspiro[4.6]undecane-8-carboxylate

Product 1

HCID 710605462-Methyl-4-phenyl-2,8-diazaspiro[4.6]undecan-1-one

Sources & evidence

ORD record
ord-dbdacf759ba045e1b0676b5a3ab2c9c5
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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