Trifluoroacetic acid → (RS)-4-[1-(2-Indan-2-yl-ethyl)-pyrrolidine-3-sulfonyl]-phenol

HRID 1149318Notes

Reaction equation

HRID 1149318 reaction equation
[CH2:23]1[CH:24]([CH2:32][CH2:33][O:34][S:35]([c:36]2[cH:37][cH:38][c:39]([CH3:40])[cH:41][cH:42]2)(=[O:43])=[O:44])[CH2:25][c:26]2[cH:27][cH:28][cH:29][cH:30][c:31]21.[F:1][C:2]([F:3])([F:4])[C:5]([OH:6])=[O:7].[NH:8]1[CH2:9][CH:10]([S:13](=[O:14])(=[O:15])[c:16]2[cH:17][cH:18][c:19]([OH:22])[cH:20][cH:21]2)[CH2:11][CH2:12]1>>[N:8]1([CH2:33][CH2:32][CH:24]2[CH2:23][c:31]3[c:26]([cH:27][cH:28][cH:29][cH:30]3)[CH2:25]2)[CH2:9][CH:10]([S:13](=[O:14])(=[O:15])[c:16]2[cH:17][cH:18][c:19]([OH:22])[cH:20][cH:21]2)[CH2:11][CH2:12]1

Participants

4

Reactant 3

HCID 6422Trifluoroacetic acidHCID 184257724-Pyrrolidin-3-ylsulfonylphenolHCID 86584021Toluene-4-sulfonic acid 2-indan-2-yl-ethyl ester

Product 1

HCID 18425794(RS)-4-[1-(2-Indan-2-yl-ethyl)-pyrrolidine-3-sulfonyl]-phenol

Sources & evidence

ORD record
ord-1070513487a0402c961f2325de30a193
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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