Chloroform → 2-(4-Benzylpiperidin-1-yl)ethan-1-amine

HRID 1149335Notes

Reaction equation

HRID 1149335 reaction equation
[C:1]([O:2][C:3](=[O:4])[NH:7][CH2:8][CH2:9][N:10]1[CH2:11][CH2:12][CH:13]([CH2:16][c:17]2[cH:18][cH:19][cH:20][cH:21][cH:22]2)[CH2:14][CH2:15]1)([CH3:5])([CH3:6])[CH3:23].[Cl:31][CH:32]([Cl:33])[Cl:34].[F:24][C:25]([F:26])([F:27])[C:28]([OH:29])=[O:30]>>[NH2:7][CH2:8][CH2:9][N:10]1[CH2:11][CH2:12][CH:13]([CH2:16][c:17]2[cH:18][cH:19][cH:20][cH:21][cH:22]2)[CH2:14][CH2:15]1

Participants

4

Reactant 3

HCID 6212ChloroformHCID 6422Trifluoroacetic acidHCID 59715914[2-(4-Benzyl-piperidin-1-yl)-ethyl]-carbamic acid tert-butyl ester

Product 1

HCID 27798312-(4-Benzylpiperidin-1-yl)ethan-1-amine

Sources & evidence

ORD record
ord-a14d84adcf8e4ce5abb03a8a5051a25f
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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