1,4-Dioxane → 2-[(2-Chloro-6,7-dihydrothieno[3,2-d]pyrimidin-4-yl)amino]-3-methylbutan-1-ol

HRID 1149545Notes

Reaction equation

HRID 1149545 reaction equation
[CH:12]([N:13]([CH:14]([CH3:15])[CH3:16])[CH2:17][CH3:18])([CH3:19])[CH3:20].[Cl:1][c:2]1[n:3][c:4]([Cl:11])[c:5]2[c:6]([n:7]1)[CH2:8][CH2:9][S:10]2.[NH2:21][CH:22]([CH2:23][OH:24])[CH:25]([CH3:26])[CH3:27].[O:28]1[CH2:29][CH2:30][O:31][CH2:32][CH2:33]1>>[Cl:1][c:2]1[n:3][c:4]([NH:21][CH:22]([CH2:23][OH:24])[CH:25]([CH3:26])[CH3:27])[c:5]2[c:6]([n:7]1)[CH2:8][CH2:9][S:10]2

Participants

5

Reactant 4

HCID 312751,4-DioxaneHCID 79019ValinolHCID 81531DiisopropylethylamineHCID 457899672,4-Dichloro-6,7-dihydrothieno[3,2-d]pyrimidine

Product 1

HCID 580715972-[(2-Chloro-6,7-dihydrothieno[3,2-d]pyrimidin-4-yl)amino]-3-methylbutan-1-ol

Sources & evidence

ORD record
ord-206c66b31fdd475cb36938d67a83f1b8
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

Loading…