Bromide ion → 1-Bromo-4-ethoxy-2,3-difluorobenzene

HRID 1149548Notes

Reaction equation

HRID 1149548 reaction equation
[Br-:16].[Br:13][CH2:14][CH3:15].[Br:3][c:4]1[c:5]([F:12])[c:6]([F:11])[c:7]([OH:10])[cH:8][cH:9]1.[CH3:17][CH2:18][CH2:19][CH2:20][N+:21]([CH2:22][CH2:23][CH2:24][CH3:25])([CH2:26][CH2:27][CH2:28][CH3:29])[CH2:30][CH2:31][CH2:32][CH3:33].[Na+:2].[OH-:1].[OH2:34]>>[Br:3][c:4]1[c:5]([F:12])[c:6]([F:11])[c:7]([O:10][CH2:14][CH3:15])[cH:8][cH:9]1

Participants

8

Reactant 7

HCID 259Bromide ionHCID 923Sodium ionHCID 961HydroxideHCID 962WaterHCID 6332Ethyl BromideHCID 16028TetrabutylammoniumHCID 102199424-Bromo-2,3-difluorophenol

Product 1

HCID 269854911-Bromo-4-ethoxy-2,3-difluorobenzene

Sources & evidence

ORD record
ord-40263862470f4166bed351fa93d666c4
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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