HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1149682Generated: October 30, 2026
1,4-Dioxane → tert-butyl 4-[5-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)pyrimidin-2-yl]-3-[(N-methylsulfonylanilino)methyl]piperazine-1-carboxylate
https://huagongshe.com/reaction/1149682
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 1,4-Dioxane | HCID 31275 | — |
| Reactant | Diisopropylethylamine | HCID 81531 | — |
| Reactant | tert-butyl 3-[(N-methylsulfonylanilino)methyl]piperazine-1-carboxylate | HCID 77891637 | — |
| Reactant | 2-(2-Chloropyrimidin-5-yl)-1,1,1,3,3,3-hexafluoropropan-2-ol | HCID 86670348 | — |
| Product | tert-butyl 4-[5-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)pyrimidin-2-yl]-3-[(N-methylsulfonylanilino)methyl]piperazine-1-carboxylate | HCID 123343268 | — |
Provenance & Evidence
| DOI | 10.1039/C8SC04228D |
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| Source dataset | Training data from https://doi.org/10.1039/C8SC04228D (7/10) |
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| ORD ID | ord-b7bf0318da914af1b5923d74ea98461e |
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| Source note | Training data from https://doi.org/10.1039/C8SC04228D (7/10) |
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