Acetic Acid → 7-Chloro-6-phenylimidazo[1,2-a]pyrimidine

HRID 1149889Notes

Reaction equation

HRID 1149889 reaction equation
[CH2:20]1[O:21][CH2:22][CH2:23][CH2:24]1.[CH3:18][OH:19].[CH3:40][C:41](=[O:42])[OH:43].[Cl:1][c:2]1[c:3](-[c:12]2[cH:13][cH:14][cH:15][cH:16][cH:17]2)[c:4]([Cl:11])[n:5][c:6]2[n:7]1[cH:8][cH:9][n:10]2.[Cu:44].[Zn:45].[c:25]1(-[c:26]2[cH:27][n:28][c:29]3[n:30]([cH:31][cH:32][n:33]3)[cH:34]2)[cH:35][cH:36][cH:37][cH:38][cH:39]1>>[cH:2]1[c:3](-[c:12]2[cH:13][cH:14][cH:15][cH:16][cH:17]2)[c:4]([Cl:11])[n:5][c:6]2[n:7]1[cH:8][cH:9][n:10]2

Participants

8

Reactant 7

HCID 176Acetic AcidHCID 887MethanolHCID 8028TetrahydrofuranHCID 23978CopperHCID 23994ZincHCID 552669136-phenyl-Imidazo[1,2-a]pyrimidineHCID 862136335,7-Dichloro-6-phenylimidazo[1,2-a]pyrimidine

Product 1

HCID 772315047-Chloro-6-phenylimidazo[1,2-a]pyrimidine

Sources & evidence

ORD record
ord-8edc3d9b36974fe2b787553ecc130187
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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