Dichloromethane → 3-Amino-6-(2,3-difluorophenyl)-1-(2,2,2-trifluoroethyl)azepan-2-one
Reaction equation
[Cl:37][CH2:38][Cl:39].[F:8][c:9]1[c:10]([CH:16]2[CH2:17][CH2:18][CH:19]([NH:29][C:30](=[O:31])[O:32][C:33]([CH3:34])([CH3:35])[CH3:36])[C:20](=[O:28])[N:21]([CH2:23][C:24]([F:25])([F:26])[F:27])[CH2:22]2)[cH:11][cH:12][cH:13][c:14]1[F:15].[OH:1][C:2]([C:3]([F:4])([F:5])[F:6])=[O:7]>>[F:8][c:9]1[c:10]([CH:16]2[CH2:17][CH2:18][CH:19]([NH2:29])[C:20](=[O:28])[N:21]([CH2:23][C:24]([F:25])([F:26])[F:27])[CH2:22]2)[cH:11][cH:12][cH:13][c:14]1[F:15]Participants
4
Sources & evidence
- ORD record
- ord-033fc43639d94b64892f134ad830b384
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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