1-Amino-2-propanol → 5-(1-aminopropan-2-yloxy)-N-[3-chloro-4-(pyridin-2-ylmethoxy)phenyl]quinazolin-4-amine
Reaction equation
[F:6][c:7]1[c:8]2[c:9]([NH:17][c:18]3[cH:19][c:20]([Cl:32])[c:21]([O:24][CH2:25][c:26]4[n:27][cH:28][cH:29][cH:30][cH:31]4)[cH:22][cH:23]3)[n:10][cH:11][n:12][c:13]2[cH:14][cH:15][cH:16]1.[NH2:1][CH2:2][CH:3]([CH3:4])[OH:5]>>[NH2:1][CH2:2][CH:3]([CH3:4])[O:5][c:7]1[c:8]2[c:9]([NH:17][c:18]3[cH:19][c:20]([Cl:32])[c:21]([O:24][CH2:25][c:26]4[n:27][cH:28][cH:29][cH:30][cH:31]4)[cH:22][cH:23]3)[n:10][cH:11][n:12][c:13]2[cH:14][cH:15][cH:16]1Participants
3
Sources & evidence
- ORD record
- ord-3225146218cf45ad9aa3dded9a2ba86f
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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