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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1150930Generated: November 2, 2026

Hydrochloric Acid → 2,2-Dimethyl-propionic acid 3-(4'-chloro-6-fluoro-4-methyl-biphenyl-3-yl)-8-methoxy-2-oxo-1,8-diaza-spiro[4.5]dec-3-en-4-yl ester

https://huagongshe.com/reaction/1150930

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantPyridineHCID 1049—
ReactantAcetonitrileHCID 6342—
ReactantPivaloyl chlorideHCID 62493—
Reactant3-(4'-Chloro-6-fluoro-4-methyl-biphenyl-3-yl)-4-hydroxy-8-methoxy-1,8-diazaspiro[4.5]dec-3-en-2-oneHCID 59614583—
Product2,2-Dimethyl-propionic acid 3-(4'-chloro-6-fluoro-4-methyl-biphenyl-3-yl)-8-methoxy-2-oxo-1,8-diaza-spiro[4.5]dec-3-en-4-yl esterHCID 58031220—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (7/10)
ORD IDord-6c07e87a3d4e455eba385f79582d6b99
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (7/10)