Hydrochloric Acid → 2,2-Dimethyl-propionic acid 3-(4'-chloro-6-fluoro-4-methyl-biphenyl-3-yl)-8-methoxy-2-oxo-1,8-diaza-spiro[4.5]dec-3-en-4-yl ester
Reaction equation
[C:30]([C:31]([CH3:32])([CH3:33])[CH3:34])(=[O:35])[Cl:36].[CH3:44][C:45]#[N:46].[Cl:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[cH:9][c:10]([C:16]3=[C:20]([OH:21])[C:19]4([NH:18][C:17]3=[O:29])[CH2:22][CH2:23][N:24]([O:27][CH3:28])[CH2:25][CH2:26]4)[c:11]([CH3:15])[cH:12][c:13]2[F:14])[cH:6][cH:7]1.[ClH:43].[cH:37]1[cH:38][cH:39][n:40][cH:41][cH:42]1>>[Cl:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[cH:9][c:10]([C:16]3=[C:20]([O:21][C:30]([C:31]([CH3:32])([CH3:33])[CH3:34])=[O:35])[C:19]4([NH:18][C:17]3=[O:29])[CH2:22][CH2:23][N:24]([O:27][CH3:28])[CH2:25][CH2:26]4)[c:11]([CH3:15])[cH:12][c:13]2[F:14])[cH:6][cH:7]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-6c07e87a3d4e455eba385f79582d6b99
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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