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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1151059Generated: October 31, 2026

Methanol → 5-Chloro-6-(tetrahydro-pyran-4-yl)-1,3-dihydro-isoindole-2-carboxylic acid tert-butyl ester

https://huagongshe.com/reaction/1151059

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethanolHCID 887—
ReactantAdams' catalystHCID 345198—
Reactant5-Chloro-6-(3,6-dihydro-2H-pyran-4-yl)-1,3-dihydro-isoindole-2-carboxylic acid tert-butyl EsterHCID 57753636—
ReactantHCID 178418361HCID 178418361—
Product5-Chloro-6-(tetrahydro-pyran-4-yl)-1,3-dihydro-isoindole-2-carboxylic acid tert-butyl esterHCID 57753503—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (7/10)
ORD IDord-375e7ac6ef5442f097af0903bbbb2c1d
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (7/10)