Methanol → 5-Chloro-6-(tetrahydro-pyran-4-yl)-1,3-dihydro-isoindole-2-carboxylic acid tert-butyl ester
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][c:10]2[cH:11][c:12]([C:18]3=[CH:23][CH2:22][O:21][CH2:20][CH2:19]3)[c:13]([Cl:17])[cH:14][c:15]2[CH2:16]1.[CH3:26][OH:27].[H:24][H:25].[Pt:28](=[O:29])=[O:30]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][c:10]2[cH:11][c:12]([CH:18]3[CH2:19][CH2:20][O:21][CH2:22][CH2:23]3)[c:13]([Cl:17])[cH:14][c:15]2[CH2:16]1Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-375e7ac6ef5442f097af0903bbbb2c1d
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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