Potassium Cation → Ethyl 2-[2-({2-chloro-4-fluoro-5-[3-methyl-2,6-dioxo-4-(trifluoromethyl)-1,2,3,6-tetrahydropyrimidine-1-yl]phenoxy}methyl)phenoxy]propionate

HRID 1151082Notes

Reaction equation

HRID 1151082 reaction equation
[Br:29][CH2:30][c:31]1[c:32]([O:33][CH:34]([C:35](=[O:36])[O:37][CH2:38][CH3:39])[CH3:40])[cH:41][cH:42][cH:43][cH:44]1.[C:23](=[O:24])([O-:25])[O-:26].[CH3:45][N:46]([CH3:47])[CH:48]=[O:49].[Cl:1][c:2]1[c:3]([OH:22])[cH:4][c:5](-[n:9]2[c:10](=[O:21])[n:11]([CH3:20])[c:12]([C:16]([F:17])([F:18])[F:19])[cH:13][c:14]2=[O:15])[c:6]([F:8])[cH:7]1.[K+:27].[K+:28]>>[Cl:1][c:2]1[c:3]([O:22][CH2:30][c:31]2[c:32]([O:33][CH:34]([C:35](=[O:36])[O:37][CH2:38][CH3:39])[CH3:40])[cH:41][cH:42][cH:43][cH:44]2)[cH:4][c:5](-[n:9]2[c:10](=[O:21])[n:11]([CH3:20])[c:12]([C:16]([F:17])([F:18])[F:19])[cH:13][c:14]2=[O:15])[c:6]([F:8])[cH:7]1

Participants

6

Reactant 5

HCID 813Potassium Cation2×HCID 6228DimethylformamideHCID 19660Carbonate IonHCID 112677571-methyl-6-trifluoromethyl-3-(4-chloro-2-fluoro-5-hydroxyphenyl)-2,4(1H,3H)-pyrimidinedioneHCID 11808300Ethyl 2-(2-bromomethylphenoxy)propionate

Product 1

HCID 18759635Ethyl 2-[2-({2-chloro-4-fluoro-5-[3-methyl-2,6-dioxo-4-(trifluoromethyl)-1,2,3,6-tetrahydropyrimidine-1-yl]phenoxy}methyl)phenoxy]propionate

Sources & evidence

ORD record
ord-fa2357df98674f9f9863d4660cf562e7
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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