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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1151339Generated: October 25, 2026

1-Bromo-3-fluorobenzene → Methyl 8-[1-(3-fluorophenyl)pyrrolidin-2-yl]-2-morpholin-4-yl-4-oxochromene-6-carboxylate

https://huagongshe.com/reaction/1151339

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Bromo-3-fluorobenzeneHCID 14082—
ReactantCarbonate IonHCID 19660—
Reactant1,4-DioxaneHCID 31275—
ReactantCesium cationHCID 104967—
Reactantpalladium(II) acetateHCID 167845—
Reactantmethyl 2-morpholino-4-oxo-8-(pyrrolidin-2-yl)-4H-chromene-6-carboxylateHCID 86672405—
ProductMethyl 8-[1-(3-fluorophenyl)pyrrolidin-2-yl]-2-morpholin-4-yl-4-oxochromene-6-carboxylateHCID 89051670—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (7/10)
ORD IDord-6e74c45543124870a4fdc3d83c1a55a9
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (7/10)