Sodium ion → 6-Difluoromethoxy-2-(4-fluoro-phenyl)-3-(4-methanesulfonyl-phenyl)-pyrazolo[1,5-b]pyridazine

HRID 1151396Notes

Reaction equation

HRID 1151396 reaction equation
[Br:30][CH:31]([F:32])[F:33].[F:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[n:9][n:10]3[n:11][c:12]([OH:27])[cH:13][cH:14][c:15]3[c:16]2-[c:17]2[cH:18][cH:19][c:20]([S:23](=[O:24])(=[O:25])[CH3:26])[cH:21][cH:22]2)[cH:6][cH:7]1.[H-:28].[Na+:29].[O:35]=[CH:36][N:37]([CH3:38])[CH3:39].[OH2:34]>>[F:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[n:9][n:10]3[n:11][c:12]([O:27][CH:31]([F:32])[F:33])[cH:13][cH:14][c:15]3[c:16]2-[c:17]2[cH:18][cH:19][c:20]([S:23](=[O:24])(=[O:25])[CH3:26])[cH:21][cH:22]2)[cH:6][cH:7]1

Participants

7

Reactant 6

HCID 923Sodium ionHCID 962WaterHCID 6228DimethylformamideHCID 62407BromodifluoromethaneHCID 166653HydrideHCID 178504660HCID 178504660, compound

Product 1

HCID 111547436-Difluoromethoxy-2-(4-fluoro-phenyl)-3-(4-methanesulfonyl-phenyl)-pyrazolo[1,5-b]pyridazine

Sources & evidence

ORD record
ord-3936394fa9f34c788d3eedf3f6929222
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

Loading…