Dichloromethane → tert-butyl N-[4-[1-acetyl-3-(trifluoromethyl)-6,8-dihydro-5H-imidazo[1,5-a]pyrazin-7-yl]-4-oxo-1-(2,4,5-trifluorophenyl)butan-2-yl]carbamate
Reaction equation
[C:17]([CH3:18])([CH3:19])([CH3:20])[O:21][C:22](=[O:23])[NH:24][CH:25]([CH2:26][C:27](=[O:28])[OH:29])[CH2:30][c:31]1[c:32]([F:39])[cH:33][c:34]([F:38])[c:35]([F:37])[cH:36]1.[CH3:40][CH2:41][N:42]([CH2:43][CH3:44])[CH2:45][CH3:46].[Cl:62][CH2:63][Cl:64].[F:1][C:2]([c:3]1[n:4][c:5]([C:12]([CH3:13])=[O:14])[c:6]2[n:7]1[CH2:8][CH2:9][NH:10][CH2:11]2)([F:15])[F:16].[O:47]=[C:48]1[N:49]([P:50]([Cl:51])([N:52]2[CH2:53][CH2:54][O:55][C:56]2=[O:57])=[O:58])[CH2:59][CH2:60][O:61]1>>[F:1][C:2]([c:3]1[n:4][c:5]([C:12]([CH3:13])=[O:14])[c:6]2[n:7]1[CH2:8][CH2:9][N:10]([C:27]([CH2:26][CH:25]([NH:24][C:22]([O:21][C:17]([CH3:18])([CH3:19])[CH3:20])=[O:23])[CH2:30][c:31]1[c:32]([F:39])[cH:33][c:34]([F:38])[c:35]([F:37])[cH:36]1)=[O:28])[CH2:11]2)([F:15])[F:16]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-16cdc2001a484169ba6f877b03c4a170
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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