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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 11518Generated: October 27, 2026

4-(3-(Diethylamino)propoxy)-3-fluoroaniline → HCID 178418944, compound

https://huagongshe.com/reaction/11518

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(3-(Diethylamino)propoxy)-3-fluoroanilineHCID 21974741—
Reactant3-(hydroxymethylidene)-1H-indol-2-oneHCID 178418741—
ProductHCID 178418944HCID 17841894424%

Reaction Steps

In a manner similar to that described in Example 231, 4-(3-Diethylamino-propoxy)-3-fluoro-phenylamine (400 mg, 1.1 equiv.) and 3-hydroxymethylene-1,3-dihydro-indol-2-one (242 mg, 1.5 mmol, 1 equiv.) are reacted to give the named compound as a yellow solid (135 mg, 24%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07098236B2
Source datasetuspto-grants-2006_08
ORD IDord-917046f5e1ea4624a55632873b38e4e0
Source noteuspto-grants-2006_08