2,2,2-Trifluoroethanol → 5-(2,2,2-Trifluoro-ethoxy)-1,3-dihydro-isoindole-2-carboxylic acid tert-butyl ester
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][c:10]2[cH:11][cH:12][c:13]([I:17])[cH:14][c:15]2[CH2:16]1.[OH:18][CH2:19][C:20]([F:21])([F:22])[F:23]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][c:10]2[cH:11][cH:12][c:13]([O:18][CH2:19][C:20]([F:21])([F:22])[F:23])[cH:14][c:15]2[CH2:16]1Participants
3
Sources & evidence
- ORD record
- ord-e439cf982f3b4e728d5f86a0f7d44a0b
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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