Tetrahydrofuran → Ethyl 4-hydroxy-1-methylcyclohexanecarboxylate

HRID 1152156Notes

Reaction equation

HRID 1152156 reaction equation
[C:1]([Si:2]([CH3:3])([CH3:4])[O:6][CH:7]1[CH2:8][CH2:9][C:10]([C:13](=[O:14])[O:15][CH2:16][CH3:17])([CH3:18])[CH2:11][CH2:12]1)([CH3:5])([CH3:19])[CH3:20].[CH2:39]1[O:40][CH2:41][CH2:42][CH2:43]1.[CH3:22][CH2:23][CH2:24][CH2:25][N+:26]([CH2:27][CH2:28][CH2:29][CH3:30])([CH2:31][CH2:32][CH2:33][CH3:34])[CH2:35][CH2:36][CH2:37][CH3:38].[F-:21]>>[OH:6][CH:7]1[CH2:8][CH2:9][C:10]([C:13](=[O:14])[O:15][CH2:16][CH3:17])([CH3:18])[CH2:11][CH2:12]1

Participants

5

Reactant 4

HCID 8028TetrahydrofuranHCID 16028TetrabutylammoniumHCID 28179Fluoride IonHCID 58230906Ethyl 4-[(tert-butyldimethylsilyl)oxy]-1-methylcyclohexanecarboxylate

Product 1

HCID 58230927Ethyl 4-hydroxy-1-methylcyclohexanecarboxylate

Sources & evidence

ORD record
ord-08ad4fea92294a01a081025749e08ed6
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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