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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1152327Generated: November 1, 2026

Tetrahydrofuran → 3-(3-Chloro-4-((pyrrolidin-1-yl)methyl)phenyl)-3-hydroxycyclobutanecarboxylic acid

https://huagongshe.com/reaction/1152327

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
Reactant3-Oxocyclobutane-1-carboxylic acidHCID 4913358—
Reactant1-(4-Bromo-2-chlorobenzyl)pyrrolidineHCID 48935414—
ReactantButyllithiumHCID 178418339—
Product3-(3-Chloro-4-((pyrrolidin-1-yl)methyl)phenyl)-3-hydroxycyclobutanecarboxylic acidHCID 57485871—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (7/10)
ORD IDord-b7d55457aa8142b9a0307f991003e26d
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (7/10)