Water → 2-(4-(1,3-Dioxan-2-yl)-2-fluorophenyl)-5-(1-phenylcyclohexyl)thiazolo[5,4-b]pyridine

HRID 1152346Notes

Reaction equation

HRID 1152346 reaction equation
[CH2:36]1[O:37][CH2:38][CH2:39][CH2:40]1.[O:2]1[CH:3]([c:8]2[cH:9][c:10]([F:35])[c:11](-[c:14]3[s:15][c:16]4[n:17][c:18]([C:23]5([c:29]6[cH:30][cH:31][cH:32][cH:33][cH:34]6)[CH2:24][CH:25]=[CH:26][CH2:27][CH2:28]5)[cH:19][cH:20][c:21]4[n:22]3)[cH:12][cH:13]2)[O:4][CH2:5][CH2:6][CH2:7]1.[OH2:1]>>[O:2]1[CH:3]([c:8]2[cH:9][c:10]([F:35])[c:11](-[c:14]3[s:15][c:16]4[n:17][c:18]([C:23]5([c:29]6[cH:30][cH:31][cH:32][cH:33][cH:34]6)[CH2:24][CH2:25][CH2:26][CH2:27][CH2:28]5)[cH:19][cH:20][c:21]4[n:22]3)[cH:12][cH:13]2)[O:4][CH2:5][CH2:6][CH2:7]1

Participants

4

Reactant 3

HCID 962WaterHCID 8028TetrahydrofuranHCID 671117662-(4-(1,3-Dioxan-2-yl)-2-fluorophenyl)-5-(1-phenylcyclohex-3-enyl)thiazolo[5,4-b]pyridine

Product 1

HCID 671117162-(4-(1,3-Dioxan-2-yl)-2-fluorophenyl)-5-(1-phenylcyclohexyl)thiazolo[5,4-b]pyridine

Sources & evidence

ORD record
ord-b8685096fcac4936b7dfe1e1be61ad34
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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