Triphenylphosphine → tert-butyl {3-[3-(2-fluorophenyl)-2,2-dioxido-2,1,3-benzothiadiazol-1(3H)-yl]-1-phenylpropyl}methylcarbamate

HRID 1152562Notes

Reaction equation

HRID 1152562 reaction equation
[F:1][c:2]1[c:3]([N:8]2[S:9](=[O:17])(=[O:18])[NH:10][c:11]3[c:12]2[cH:13][cH:14][cH:15][cH:16]3)[cH:4][cH:5][cH:6][cH:7]1.[OH:38][CH2:39][CH2:40][CH:41]([c:42]1[cH:43][cH:44][cH:45][cH:46][cH:47]1)[N:48]([C:49]([O:50][C:51]([CH3:52])([CH3:53])[CH3:54])=[O:55])[CH3:56].[c:19]1([P:20]([c:21]2[cH:22][cH:23][cH:24][cH:25][cH:26]2)[c:27]2[cH:28][cH:29][cH:30][cH:31][cH:32]2)[cH:33][cH:34][cH:35][cH:36][cH:37]1>>[F:1][c:2]1[c:3]([N:8]2[S:9](=[O:17])(=[O:18])[N:10]([CH2:39][CH2:40][CH:41]([c:42]3[cH:43][cH:44][cH:45][cH:46][cH:47]3)[N:48]([C:49]([O:50][C:51]([CH3:52])([CH3:53])[CH3:54])=[O:55])[CH3:56])[c:11]3[c:12]2[cH:13][cH:14][cH:15][cH:16]3)[cH:4][cH:5][cH:6][cH:7]1

Participants

4

Reactant 3

HCID 11776TriphenylphosphineHCID 468330941-(2-Fluorophenyl)-1,3-dihydro-2,1,3-benzothiadiazole 2,2-dioxideHCID 71967731Tert-butyl (3-hydroxy-1-phenylpropyl)methylcarbamate

Product 1

HCID 86621286tert-butyl {3-[3-(2-fluorophenyl)-2,2-dioxido-2,1,3-benzothiadiazol-1(3H)-yl]-1-phenylpropyl}methylcarbamate

Sources & evidence

ORD record
ord-f9e6cd9376fe4f1f862767c9eeaca167
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

Loading…