Methanol → Trifluoroacetic acid

HRID 1152569Notes

Reaction equation

HRID 1152569 reaction equation
[CH3:46][OH:47].[F:1][C:2]([C:3](=[O:4])[OH:5])([F:6])[F:7].[NH2:8][CH2:9][CH2:10][CH2:11][n:12]1[cH:13][c:14](-[n:22]2[c:23](=[O:45])[nH:24][n:25][c:26]2-[c:27]2[cH:28][n:29]([CH3:44])[c:30]3[cH:31][c:32]([O:36][CH2:37][c:38]4[cH:39][cH:40][cH:41][cH:42][cH:43]4)[cH:33][cH:34][c:35]23)[c:15]2[cH:16][c:17]([F:21])[cH:18][cH:19][c:20]12.[Pd:48]>>[F:1][C:2]([C:3](=[O:4])[OH:5])([F:6])[F:7].[NH2:8][CH2:9][CH2:10][CH2:11][n:12]1[cH:13][c:14](-[n:22]2[c:23](=[O:45])[nH:24][n:25][c:26]2-[c:27]2[cH:28][n:29]([CH3:44])[c:30]3[cH:31][c:32]([OH:36])[cH:33][cH:34][c:35]23)[c:15]2[cH:16][c:17]([F:21])[cH:18][cH:19][c:20]12

Participants

6

Reactant 4

HCID 887MethanolHCID 6422Trifluoroacetic acidHCID 23938PalladiumHCID 18385300HCID 18385300, compound

Product 2

HCID 6422Trifluoroacetic acidHCID 18385309HCID 18385309, compound

Sources & evidence

ORD record
ord-da61a5dc43774033bb3f82eaba43ceb0
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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