Hydrochloric Acid → Tert-butyl 3-[[4-[2,2-dimethylpropyl(methyl)amino]-6-[2-methyl-5-(methylcarbamoyl)anilino]pyrimidin-2-yl]amino]pyrrolidine-1-carboxylate
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH:10]([NH:13][c:14]2[n:15][c:16]([NH:21][c:22]3[c:23]([CH3:32])[cH:24][cH:25][c:26]([C:28]([NH:29][CH3:30])=[O:31])[cH:27]3)[cH:17][c:18]([F:20])[n:19]2)[CH2:11][CH2:12]1.[CH2:41]1[O:42][CH2:43][CH2:44][O:45][CH2:46]1.[CH3:34][NH:35][CH2:36][C:37]([CH3:38])([CH3:39])[CH3:40].[ClH:33]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH:10]([NH:13][c:14]2[n:15][c:16]([NH:21][c:22]3[c:23]([CH3:32])[cH:24][cH:25][c:26]([C:28]([NH:29][CH3:30])=[O:31])[cH:27]3)[cH:17][c:18]([N:35]([CH3:34])[CH2:36][C:37]([CH3:38])([CH3:39])[CH3:40])[n:19]2)[CH2:11][CH2:12]1Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-601c5c2a17fe4a3ba866f979a6fa1cfb
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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