Tetrahydrofuran → Tert-butyl 4-(2-oxopropyl)piperidine-1-carboxylate
Reaction equation
[CH2:24]1[O:25][CH2:26][CH2:27][CH2:28]1.[CH3:1][Mg:2][Cl:3].[CH3:4][O:5][N:6]([C:7]([CH2:8][CH:9]1[CH2:10][CH2:11][N:12]([C:15](=[O:16])[O:17][C:18]([CH3:19])([CH3:20])[CH3:21])[CH2:13][CH2:14]1)=[O:22])[CH3:23]>>[CH3:1][C:7]([CH2:8][CH:9]1[CH2:10][CH2:11][N:12]([C:15](=[O:16])[O:17][C:18]([CH3:19])([CH3:20])[CH3:21])[CH2:13][CH2:14]1)=[O:22]Participants
4
Sources & evidence
- ORD record
- ord-b0a3c2c7e3e74ed1910f9f92c19497fb
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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