Acetone → 3-[(3-Chloro-4-trifluoromethoxy-phenyl)-(2-hydroxy-ethyl)-amino]-propionic acid tert-butyl ester
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([CH2:7][CH2:8][N:9]([CH2:10][C:11](=[O:12])[O:13][CH3:14])[c:15]1[cH:16][c:17]([Cl:26])[c:18]([O:21][C:22]([F:23])([F:24])[F:25])[cH:19][cH:20]1)=[O:27].[CH2:34]1[O:35][CH2:36][CH2:37][CH2:38]1.[CH2:39]1[CH2:40][CH2:41][CH2:42][CH2:43][CH2:44]1.[CH3:28][OH:29].[CH3:30][C:31](=[O:32])[CH3:33].[Na+:46].[OH-:45]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([CH2:7][CH2:8][N:9]([CH2:10][CH2:11][OH:12])[c:15]1[cH:16][c:17]([Cl:26])[c:18]([O:21][C:22]([F:23])([F:24])[F:25])[cH:19][cH:20]1)=[O:27]Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-b557d452df784e4c81ec01c54ab34f4a
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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