Ethylene Glycol → 2,4-Dichloro-6-(3-[1,3]dioxolan-2-yl-5-methyl-phenoxy)-5-isopropyl-pyrimidine

HRID 1153147Notes

Reaction equation

HRID 1153147 reaction equation
[CH3:37][c:38]1[cH:39][cH:40][cH:41][cH:42][cH:43]1.[Cl:1][c:2]1[n:3][c:4]([Cl:21])[c:5]([CH:18]([CH3:19])[CH3:20])[c:6]([O:8][c:9]2[cH:10][c:11]([CH:12]=[O:13])[cH:14][c:15]([CH3:17])[cH:16]2)[n:7]1.[OH:22][CH2:23][CH2:24][OH:25].[c:26]1([CH3:27])[cH:28][cH:29][c:30]([S:31]([OH:32])(=[O:33])=[O:34])[cH:35][cH:36]1>>[Cl:1][c:2]1[n:3][c:4]([Cl:21])[c:5]([CH:18]([CH3:19])[CH3:20])[c:6]([O:8][c:9]2[cH:10][c:11]([CH:12]3[O:13][CH2:24][CH2:23][O:22]3)[cH:14][c:15]([CH3:17])[cH:16]2)[n:7]1

Participants

5

Reactant 4

HCID 174Ethylene GlycolHCID 1140TolueneHCID 6101p-Toluenesulfonic acidHCID 591846443-(2,6-Dichloro-5-isopropyl-pyrimidin-4-yloxy)-5-methyl-benzaldehyde

Product 1

HCID 591847212,4-Dichloro-6-(3-[1,3]dioxolan-2-yl-5-methyl-phenoxy)-5-isopropyl-pyrimidine

Sources & evidence

ORD record
ord-28a7d4a8c0dd4a54bab7e51fe474a57d
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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