Dimethylformamide → N-Cyclopropyl-4-fluoro-2-(2-oxiranylmethoxy)benzamide

HRID 1153167Notes

Reaction equation

HRID 1153167 reaction equation
[C:32](=[O:33])([O-:34])[O-:35].[CH:1]1([NH:4][C:5]([c:6]2[c:7]([OH:13])[cH:8][c:9]([F:12])[cH:10][cH:11]2)=[O:14])[CH2:2][CH2:3]1.[Cs+:36].[Cs+:37].[O:15]1[CH:16]([CH2:18][O:19][S:20]([c:21]2[cH:22][cH:23][cH:24][c:25]([N+:26]([O-:27])=[O:28])[cH:29]2)(=[O:30])=[O:31])[CH2:17]1.[O:38]=[CH:39][N:40]([CH3:41])[CH3:42]>>[CH:1]1([NH:4][C:5]([c:6]2[c:7]([O:13][CH2:18][CH:16]3[O:15][CH2:17]3)[cH:8][c:9]([F:12])[cH:10][cH:11]2)=[O:14])[CH2:2][CH2:3]1

Participants

6

Reactant 5

HCID 6228DimethylformamideHCID 19660Carbonate IonHCID 104967Cesium cation2×HCID 286836(Oxiran-2-yl)methyl 3-nitrobenzene-1-sulfonateHCID 68961144N-Cyclopropyl-4-fluoro-2-hydroxybenzamide

Product 1

HCID 45086863N-Cyclopropyl-4-fluoro-2-(2-oxiranylmethoxy)benzamide

Sources & evidence

ORD record
ord-55624d48e15c465cacf798b112347bbe
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

Loading…