Dichloromethane → Methyl 1,2,3,4-tetrahydroisoquinoline-7-carboxylate

HRID 1153592Notes

Reaction equation

HRID 1153592 reaction equation
[CH2:1]1[N:2]([C:15]([O:16][C:17]([CH3:18])([CH3:19])[CH3:20])=[O:21])[CH2:3][CH2:4][c:5]2[cH:6][cH:7][c:8]([C:11](=[O:12])[O:13][CH3:14])[cH:9][c:10]21.[Cl:29][CH2:30][Cl:31].[OH:22][C:23]([C:24]([F:25])([F:26])[F:27])=[O:28]>>[CH2:1]1[NH:2][CH2:3][CH2:4][c:5]2[cH:6][cH:7][c:8]([C:11](=[O:12])[O:13][CH3:14])[cH:9][c:10]21

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 594838422-Tert-butyl 7-methyl 3,4-dihydroisoquinoline-2,7(1H)-dicarboxylate

Product 1

HCID 10656920Methyl 1,2,3,4-tetrahydroisoquinoline-7-carboxylate

Sources & evidence

ORD record
ord-cd081798ccb04907be175358897f3905
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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