Dichloromethane → Benzyl 3-[3-(5-cyano-2-methoxyphenyl)prop-2-enoylamino]-4-[4-(4-fluorophenoxy)piperidin-1-yl]butanoate
Reaction equation
[B-:23]([F:24])([F:25])([F:26])[F:27].[C:1](#[N:2])[c:3]1[cH:4][cH:5][c:6]([O:14][CH3:15])[c:7]([CH:9]=[CH:10][C:11](=[O:12])[OH:13])[cH:8]1.[CH2:45]([c:46]1[cH:47][cH:48][cH:49][cH:50][cH:51]1)[O:52][C:53]([CH2:54][CH:55]([CH2:56][N:57]1[CH2:58][CH2:59][CH:60]([O:63][c:64]2[cH:65][cH:66][c:67]([F:70])[cH:68][cH:69]2)[CH2:61][CH2:62]1)[NH2:71])=[O:72].[CH3:16][CH2:17][N:18]([CH2:19][CH3:20])[CH2:21][CH3:22].[Cl:73][CH2:74][Cl:75].[n:28]1([O:29][C:30]([N:31]([CH3:32])[CH3:33])=[N+:34]([CH3:35])[CH3:36])[c:37]2[cH:38][cH:39][cH:40][cH:41][c:42]2[n:43][n:44]1>>[C:1](#[N:2])[c:3]1[cH:4][cH:5][c:6]([O:14][CH3:15])[c:7]([CH:9]=[CH:10][C:11](=[O:13])[NH:71][CH:55]([CH2:54][C:53]([O:52][CH2:45][c:46]2[cH:47][cH:48][cH:49][cH:50][cH:51]2)=[O:72])[CH2:56][N:57]2[CH2:58][CH2:59][CH:60]([O:63][c:64]3[cH:65][cH:66][c:67]([F:70])[cH:68][cH:69]3)[CH2:61][CH2:62]2)[cH:8]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-4ff877cfe693471898b2b1d05d0729b3
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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