反应详情

A stirred solution of 0.238 g of (1A), 0.15 g of N-chlorosuccinimide and about 1 mg of azoisobutyronitrile in 10 ml of dichloroethane was refluxed overnight. The resulting mixture was cooled, washed with water, dried (MgSO4) and stripped of solvent, giving a yellow oil. The oil was flash-chromatographed over silica gel, using methylene chloride as eluent, to give (2).

1. temperatureThe resulting mixture was cooled
2. washwashed with water
3. dry with materialdried (MgSO4)
4. customgiving a yellow oil
5. customThe oil was flash-chromatographed over silica gel