Formic Acid → HCID 13075532, compound

HRID 1153969Notes

Reaction equation

HRID 1153969 reaction equation
[I:1][C:2](=[C:5]([I:7])[I:6])[CH2:3][OH:4].[CH:8](O)=[O:9]>>[CH:8]([O:4][CH2:3][C:2]([I:1])=[C:5]([I:7])[I:6])=[O:9]

Participants

3

Reactant 2

HCID 284Formic AcidHCID 102167312,3,3-Triiodo-2-propen-1-ol

Product 1

HCID 13075532HCID 13075532, compound

Procedure

2.0 g of 2,3,3-triiodoallyl alcohol and 30 ml of formic acid were refluxed, with stirring, for 3 hours. After cooling the mixture, the crystals which precipitated were collected by filtration, dissolved in ethyl acetate, adsorbed in a dry silica gel chromatography column and eluted with 3:1 by volume mixture of hexane and ethyl acetate, to give 1.8 g of the desired Compound No. 81 in the form of crystals melting at 84°-85° C.

Workup

  1. temperatureAfter cooling the mixture
  2. customthe crystals which precipitated
  3. filtrationwere collected by filtration
  4. dissolutiondissolved in ethyl acetate
  5. washeluted with 3:1 by volume mixture of hexane and ethyl acetate

Sources & evidence

ORD record
ord-9967c43190c74e3fbd834ca8706d02c5
Source dataset
uspto-grants-1984_12
Patent number
US04487781

Reaction notes

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