HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 6-[3-(1-Pyrrolidinyl)propylamino]-7,8,9,10-tetrahydro-1,2,4-triazolo[3,4-a]phthalazine dihydrochloride hemihydrate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Ethanol | HCID 702 | — |
| Reactant | 6-[3-(1-Pyrrolidinyl)propylamino]-7,8,9,10-tetrahydro-1,2,4-triazolo[3,4-a]phthalazine | HCID 13365600 | — |
| Product | 6-[3-(1-Pyrrolidinyl)propylamino]-7,8,9,10-tetrahydro-1,2,4-triazolo[3,4-a]phthalazine dihydrochloride hemihydrate | HCID 70503725 | — |
Reaction Steps
The amine obtained above was dissolved in ethanol and treated with an excess of ethereal hydrogen chloride. The solid which formed was separated by filtration to give 6-[3-(1-pyrrolidinyl)propylamino]-7,8,9,10-tetrahydro-1,2,4-triazolo[3,4-a]phthalazine dihydrochloride hemihydrate melting at about 277°-278° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04487930 |
| Source dataset | uspto-grants-1984_12 |
| ORD ID | ord-c1c1568c8cbf45c0b3738e0c5c8a424e |
| Source note | uspto-grants-1984_12 |